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Pituitary Dysfunction after Pediatric TBI

According to an article in Volume 15, Issue 3 of the journal Pituitary published in Sept. 2012 there is evidence that about 30% of all children who suffer a traumatic brain injury show reduced pituitary output for up to 5 years post-injury. Hypopituitarism in children can be accompanied by reduced output of HGH (human growth hormone), stunted growth, and failure to develop normally during puberty. If the hypothalamus is damaged as a result of pediatric TBI the child can develop ACTH deficiency, diabetes insipidus, hypothyroidism or elevated prolactin. Given the serious consequences of endocrine disturbance post-TBI in children, it is recommended that children be monitored for such changes for at least one year post-TBI.

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