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HYPERSOMNIA
Hypersomnia is a state of excessive somnolence, in which an
adult will sleep as much, or more, than 16 hours a day (the
same pattern as newborns). It afflicts a smaller number of
TBI patients than insomnia (inability to get to sleep or stay
asleep). However, for those affected it is a huge problem,
because they have very limited periods of wakefulness. After
attending to feeding and hygiene, they have very little time
left for therapy or productive activities. Rehab professionals
would deal with such a patient by trying to keep them mentally
stimulated through activity. Medications which boost dopamine
or norepinephrine are sometimes tried.
The new medication for narcolepsy called Modafanil might hold
some promise. During Feb. 2001 the New York Times reported
that people in Africa who came down with sleeping sickness
had responded remarkably well to a drug called eflornithine,
which ironically is used as an ingredient in a cream called
Vaniqa made by Bristol-Myers & Gillette which removes
facial hair by suppressing the skin enzyme responsible for
its growth. Apparently the drug helps rouse stuporous, even
comatose, patients by killing the parasite (trypanosome) after
it has invaded the brain. Does eflornithine do more, i.e.
stimulate the brain to wakefulness? This could be a fruitful
area of research.
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