| PET
SCAN [ back
to Glossary Index ]
PET Scan or positron emission tomography is a non-inasive
neuro-imaging technique which works on the premise that healthy
brain cells will metabolize much more glucose during mental
tasks than damaged, dying or dead brain cells. The brain is
a highest user of glucose and oxygen than any other
organ in the body. The patient undergoing a PET scan receives
an IV drip of glucose tagged with a radio-isotope tracer,
performs specified mental tasks for about 20 minutes and then
places his head inside a "gamma camera." When the
positrons (positively charged subatomic particles) in the
glucose are "taken up" into activated brain cells
and come into contact with negatively charged electrons, they
neutralize each other and send gamma rays off in exactly opposite
directions. The gamma rays emitted from the brain are picked
up by the camera and fed instantly into a powerful computer
which will reconstruct the spatio-temporal pattern in a 3
dimensional, color coded map depicting how the brain is functioning.
Different shades of color correlate with differing levels
of brain activity in different regions of the brain, and are
used to visually highlight even the most subtle disturbances
in the expected levels of brain metabolism for a given person
(according to comparisons with controls matched for age, gender,
etc). An example of a PET scan may be found on the Welcome
Page of this website. To increase accuracy the patient is
weaned off any drugs he was taking for medical conditions
during the week preceding the test, because those drugs may
change and complicate the picture of how the unmedicated brain
is performing it's job.
PET scans cost in the area of $2,500 to $3,000. They were
originally used to diagnose metastatic cancer and heart disease,
but have been used with great frequency to study disturbances
of normal brain function in the past two decades in
both the the research and clinical settings, including the
diagnosis of persons with schizophrenia and mood disorders
as well as the planning of rehabilitation for persons with
a TBI. While
insurance company "experts" assert in TBI litigation
that PET scans are still a purely experimental research technique
unproven in clinical medicine, this is false. Health insurance
companies across the United States pay for them to be done
on a regular basis in the diagnosis and rehabilitation of
persons with brain injuries from cancer, stroke and trauma
too. Experts in the interpretation of PET scans have charted
different "activation patterns" of the brains of
persons with a variety of neurologic and psychiatric disturbances,
and have acquired a huge data base which can be used for comparison
purposes.
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