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Radiological Proof that MTBI Reduces Working Memory

In the September 2012 issue of the journal Radiology Taiwanese researchers present a study on 20 patients with mild TBI and 18 healthy controls which shows deficits in working memory in the mild TBI patients. While being scanned by a functional MRI machine, the test subjects underwent a series of memory tests involving number sequences, and the ability to sustain attention and use selective attention.

As the memory tests got harder the mild TBI patients did worse than the healthy controls, and unlike the healthy controls their level of neural network activation in their frontal lobes did not increase with increased task difficulty. This constitutes evidence that mild TBI interferes with and limits working memory for a period of time following injury.