Cyclosporine Effectively Treats Severe TBI

NeuroVive Pharmaceutical, AB is a Swedish drug development company. Working with NeuroStat it has developed a mechanism for delivering drugs directly to the brain through the blood-brain-barrier which normally screens out large molecules. In recent tests NeuroVive has shown that cyclosporine A, a drug used to help organ transplant recipients avoid immune rejection, helps victims of severe traumatic brain injury by revving up the shocked mitochondria in their brain cells. Mitochondria are the part of cells that produce the vital energy needed for all cellular processes including cellular respiration, repair, and reproduction. NeuroVive continues to work on this new treatment, and it has just received a large grant from the Swedish government to use cyclosporine to treat acute stroke.